Table 1. Baseline clinical, hemodynamic and laboratory variables of patients without and with angina.
| Without Angina n = 3714 |
With Angina n = 1356 |
P value | |
|---|---|---|---|
| Age (years), mean±SD | 67.3±10.9 | 68.3±9.5 | 0.002 |
| Age >75 years, n (%) | 948 (25.5) | 335 (24.7) | 0.55 |
| Females, n (%) | 713 (19.2) | 295 (21.8) | 0.04 |
| BMI (kg/m2), mean±SD | 27.4±4.0 | 27.3±3.9 | 0.56 |
| Active smokers, n (%) | 675 (18.2) | 212 (15.6) | 0.04 |
| Hypercholesterolemia, n (%) | 2767 (74.5) | 1023 (75.4) | 0.50 |
| Diabetes mellitus, n (%) | 1092 (29.4) | 466 (34.4) | 0.0007 |
| Hypertension, n (%) | 2890 (77.8) | 1134 (83.6) | <0.0001 |
| History of Atrial Fibrillation, n (%) | 548 (14.8) | 147 (10.8) | 0.0003 |
| Chronic renal dysfunction, n (%) | 475 (12.8) | 127 (9.4) | 0.0009 |
| Peripheral artery disease, n (%) | 292 (7.9) | 159 (11.7) | <0.0001 |
| COPD, n (%) | 458 (12.3) | 145 (10.7) | 0.11 |
| Sleep apnea, n (%) | 128 (3.5) | 35 (2.6) | 0.12 |
| Malignancy, n (%) | 237 (6.4) | 94 (6.9) | 0.48 |
| Depression, n (%) | 422 (11.4) | 109 (8.0) | 0.0006 |
| Previous stroke/TIA, n (%) | 195 (5.3) | 81 (6.0) | 0.32 |
| History of major bleeding events, n (%) | 72 (1.9) | 23 (1.7) | 0.57 |
| History of heart failure, n (%) | 562 (15.1) | 118 (8.7) | <0.0001 |
| Prior ACS, n (%) | 2980 (80.2) | 444 (32.7) | <0.0001 |
| Previous revascularization, n (%) | 3189 (85.9) | 777 (57.3) | <0.0001 |
| Ejection fraction (%), mean±SD available for 4599 (90.7%) pts |
53.3±10.3 | 55.7±8.7 | <0.0001 |
| SBP (mmHg), mean±SD | 129.6±16.5 | 131.4±16.3 | 0.0004 |
| HR (bpm), mean±SD | 66.0±10.9 | 65.4±10.6 | 0.09 |
| Atrial fibrillation at entry ECG, n (%) | 163 (4.4) | 48 (3.5) | 0.18 |
| Hb (gr/dl), mean±SD available for 4139 (81.6%) pts |
13.6±1.8 | 13.6±1.6 | 0.34 |
| Creatinine (mg/dl), mean±SD available for 4130 (81.5%) pts |
1.09±0.57 | 1.04±0.56 | 0.003 |
| Total cholesterol (mg/dl), mean±SD available for 3669 (72.4%) pts |
152.2±38.4 | 161.2±40.0 | <0.0001 |
| LDL cholesterol (mg/dl), mean±SD available for 3210 (63.3%) pts |
85.8±33.7 | 91.4±34.0 | <0.0001 |
| Triglycerides (mg/dl), median (IQR) available for 3557 (70.2%) pts |
110 (83–149) | 116 (86–164) | 0.002 |
| Glycemia (mg/dl), mean±SD available for 3778 (74.5%) pts |
113.8±36.0 | 113.6±36.5 | 0.89 |
ACS: acute coronary syndrome (STEMI or NSTE-ACS); BMI: body mass index; COPD: chronic obstructive pulmonary disease; ECG: electrocardiogram; Hb: hemoglobin; HR: heart rate; LDL: low density lipoprotein; SBP: systolic blood pressure; TIA: transient ischemic attack.