Table 7. Association of LPR gene polymorphism with clinical, body composition, anthropometry and biochemical parameters.
| Variables | OSA (n = 171) | Non OSA (n = 69) | ||||
|---|---|---|---|---|---|---|
| Q/Q | Q/R | R/R | Q/Q | Q/R | R/R | |
| Numbers (%) | 110 (64.3) | 43 (25.1) | 18(10.6) | 49 (71) | 16 (23.2) | 4 (5.8) |
| Age (yrs) | 45.6±9.0 | 452±10.6 | 46.2±10.1 | 41.1±13.0 | 41.7±11 | 40.7±11.8 |
| SYBP (mmHg) | 133.6±12.9 | 133.2±13.1 | 132.6±13.1 | 132.0±17.5 | 131.1±8.3 | 130.1±8.6 |
| DYSBP (mmHg) | 86.3±8.3 | 85.9±11.3 | 85.4±17.5 | 85±9.1 | 84±6.4 | 85.3±6.9 |
| BMI (kg/m2) | 38.0±14.5 | 39.4±12.9 | 39.1±11.0 | 31.7±6.9 | 32±8.1 | 31.9±8.6 |
| Fat mass (kg) | 38.1±17.1 | 40.7±9.3 | 44.3±9.6* | 36.2±16.6 | 33.1±15.1 | 34.1±15.2 |
| FFM (kg) | 54.5±13.0 | 50.2±10.1 | 53.2±10.7 | 46.8±12.7 | 48.5±10.2 | 50.9±10.3 |
| Body fat (%) | 35.9±12.0 | 36.5±10.1 | 38.5±11.7* | 39.0±11.5 | 40.1±14.1 | 41.2±14.2 |
| Circumferences (cm) | ||||||
| WC | 104.7±11.4 | 106±14 | 108.6±16.0* | 101.7±13.6 | 102±11.1 | 104±11.9 |
| HC | 105.9±11.6 | 107±14.2 | 110.7±19.2* | 104.6±11.1 | 103.1±16.2 | 104.3±15.2 |
| MTC | 55.6±12.7 | 56.7±12.1 | 58.1±14.2* | 51.1±10.6 | 52.1±12.1 | 53.4±12.2 |
| MAC | 28.3±5.0 | 30.7±7.1 | 30.9±7.2 | 28.2±5.0 | 29.7±5.2 | 28.9±5.3 |
| NC | 37.5±6.8 | 38.1±4.1 | 39.4±4.7 | 36.0±4.2 | 35.8±3.1 | 36.5±3.6 |
| Skinfolds (mm) | ||||||
| Biceps | 17.7±7.2 | 15.9±6.5 | 15.4±6.5 | 14±6.5 | 17.8±21.0 | 18.6±22.0 |
| Triceps | 22.9±9.10 | 25.2±9.8 | 26.2±10.3 | 22.2±9.4 | 21.5±9.1 | 22.2±9.2 |
| Sub Scapular | 28.1±8.9 | 29.8±7.1 | 31.0±8.1* | 26.1±9.6 | 25.9±9.1 | 27.4±9.2 |
| Anti axillary | 16.9±5.7 | 17.3±6.1 | 16.5±6.3 | 13.3±5.4 | 12.9±4.2 | 13.0±4.9 |
| Suprailiac | 30.2±9.2 | 31.2±8.2 | 32.8±8.4 | 27.8±7.6 | 29.1±8.3 | 30.1±8.6 |
| Lateral Thoracic | 31.3±10.1 | 40.5±6.1 | 44.5±61.8* | 30.7±9.6 | 31.5±10.2 | 33.1±10.4 |
| Thigh ( | 26.4±9.6 | 24.5±10.1 | 25.0±10.4 | 25.3±8.9 | 24.7±6.3 | 23.5±6.0 |
| FBG (mg/dl) | 103.8±24.6 | 102.4±26.1 | 103.1±26.5 | 98.6±24.6 | 97±11.2 | 96.9±10.6 |
| TG (mg/dl) | 150.9±70.4 | 167±70.4 | 172.4±77.1* | 172.4±94.8 | 168±40.8 | 163.5±46.5* |
| TC (mg/dl) | 179.5±53.4 | 180±36.1 | 182.0±37.2* | 165.6±24.5 | 183.0±41.2 | 193.0±44.0* |
| HDL-C (mg/dl) | 42.6±8.2 | 41.6±8.1 | 41.9±8.2 | 43±4.7 | 44±10.1 | 45.3±10.5 |
| LDL-C (mg/dl) | 113.9±47.4 | 111±34 | 110.4±34.2 | 95.3±21.5 | 101±38.4 | 115.1±39.9* |
| VLDL (mg/dl) | 29.4±13.9 | 30.3±11.1 | 31.1±11.8 | 29.4±9.4 | 34.7±18.2 | 32.8±19.1 |
| ALT (IU/L) | 39.3±25.3 | 40.10±32.1 | 42.0±33.1* | 36.3±16.9 | 39.0±20.2 | 42.0±21.6* |
| AST (IU/L) | 45.5±31.6 | 49.4±32.0 | 50.0±32.1* | 47.1±41.4 | 49.0±40.1 | 53.4±41.4 |
| ALK (IU/L) | 177.8±89.4 | 186.2±89.9 | 195.4±91.5* | 182.7±58.0 | 201.5±78.2 | 212.5±82.9 |
| Insulin (μU/ml) | 10.8±6.9 | 11.5±7.3 | 12.5±7.5 | 8.5±4.2 | 9.1±4.1 | 9.6±4.2 |
| Leptin (ng/ml) | 17.9±9.3 | 19.3±11.1 | 21.3±10.3* | 19.8±11.7 | 19.8±8.1 | 20.3±8.5 |
| Adiponectin (μg/ml) | 14.2±6.3 | 13.2±5.3 | 12.4±5.5 | 13.5±5.8 | 13.2±3.1 | 13.5±3.5 |
| IL-6 (pg/ml) | 15.5±9.3 | 21.0±8.2* | 23.0±7.6* | 11.2±6.3 | 19.3±8.1 | 19.4±8.6* |
Results are shown as mean± SD.
*P value is <0.05 is statistically significant. SYBP, systolic blood pressure; DYBP, diastolic blood pressure, WC, waist circumference; BMI, body mass index; FFM, fat free mass; HC hip circumference; MTC, mid thigh circumference; MAC, mid arm circumference; NC, neck circumference; FBG, fasting blood glucose; TG, triglyceride; TC, total cholesterol; HDL, high density lipoprotein; VLDL, very low density lipoprotein; ALP, Alkaline phosphate; ALT, alanine transaminase; AST, aspartate transaminase; IL-6, Interleukin-6.