Fig 7. Altered serotonergic innervation of the reeler hippocampus at P20.
(A) Expression of Cxcr4-eGFP in Cajal-Retzius (CR) cells of the dentate gyrus. (B-D) Serotonergic fibers are distributed throughout hippocampal layers, and 5-HT positive fibers and Cajal-Retzius cells overlap. (E) Scattered distribution of Cajal-Retzius cells in reeler hippocampus. (F-H) Severe reduction of serotonergic fibers in Cxcr4-eGFP hippocampal reeler mice. CA1, cornu ammonis area 1; CA3, cornu ammonis area 3; DG, dentate gyrus. Scale bar for A-D: 100μm.