Fig 8. Altered serotonergic innervation of cerebellum in reeler mutants at P20.
(A-C) 5-HT positive fibers in the wild type cerebellum extend into the granule cell layer and Purkinje cell layer as well as to the outer molecular layer. (D-F) 5-HT positive fibers in the reeler cerebellum extend only to Purkinje cell layer, which are aberrantly located in the cerebellar white matter and 5-HT fibers do not reach to reeler granule cells and outer molecular cell layer. PCL. Purkinje cell layer; IGL. Inner granular layer; OML. Outer molecular layer; GL. Granule cell layer. Scale bar A-D: 100μm.