Table 2:

Molecules and pathways associated with Planarian regeneration.

Molecules/pathway	Planarian physiology	References
The WNT/β-Catenin pathway regulates the Planarian anterioposterior (AP)axis.	Regeneration and homeostasis	[4]
Bone morphogenetic proteins (BMP)/Decapentaplegic (Dpp) proteins homolgoues are essential in Dorsoventral (DV) partitioning.
WntA is important for the patterning of the posterior brain
The planarian BMP/anti-dorsalizing morphogenetic protein (ADMP) circuit is regulated by canonical antagonists of the noggin family and novel noggin-like genes (nlg).	DV axis regeneration	[5]
Gap Junction (GJ) proteins are essential regulators of neoblast biology	Neoblast Biology	[6]
Innexin proteins modulate neoblast responses
Three major Piwi proteins: SMEDWI-1, 2 and -3 in Schmidtea mediterranea and DJPIWI A, B and C in Dugesia Japonica important in neoblast function		[7]