Key resources table.

Reagent type (species) or resource	Designation	Source and reference	Identifiers
Strain, strain background (S. cerevisiae)	Strain background: BY4741	Open Biosystems	Cat#YSC1048
Strain, strain background (S. cerevisiae)	Strain background: BY4742	Open Biosystems	Cat#YSC1049
Strain, strain background (S. cerevisiae)	Strain background: YBL574	Nakanishi et al. 2008, PMID: 18622391	N/A
Antibody	Anti H3pT11	Abcam	Cat# ab5168, RRID:AB_304759
Antibody	Anti H3	Abcam	Cat#Ab1791 RRID:AB_302613
Antibody	Anti H3K4me3	EMD Millipore	Cat#07–473 RRID:AB_1977252
Antibody	Anti H4K16ac, Rabbit polyclonal	Huang et al., 2014 PMID: 25512562	N/A
Antibody	Anti CBP, Rabbit polyclonal	Venkatesh et al., 2012 PMID: 22914091	N/A
Recombinant DNA reagent	pFA6A-NatMX6	Euroscarf	Cat#P30437
Recombinant DNA reagent	pFA6a-6xGLY-V5- kanMX6	Addgene	Cat#20780
Commercial assay or kit	KAPA HTP library prep kit	KAPA Biosystems	Cat#KK8234
Commercial assay or kit	TruSeq Stranded Total RNA Library Prep Kit with Ribo-Zero Gold set B	Illumina	Cat#RS-122–2302
Commercial assay or kit	HiSeq SR Cluster Kit v4 cBot	Illumina	Cat#GD-401–4001
Commercial assay or kit	HiSeq SBS Kit v4 (50 cycles)	Illumina	Cat#FC-401–4001
Commercial assay or kit	Glucose Colorimetric Detection Kit	ThermoFisher Scientific	Cat#EIAGLUC
Commercial assay or kit	Acetate Colorimetric Assay Kit	Sigma-Aldrich	Cat#MAK086
Software, algorithm	bcl2fastq 1.8.4	Illumina	RRID:SCR_015058
Software, algorithm	bowtie2 (2.2.0)	PMID: 22388286	RRID:SCR_005476
Software, algorithm	R (3.2.2)	https://www.R-project.org/.	RRID:SCR_001905
Software, algorithm	DiffBind (2.0.9)	PMID: 22217937	RRID:SCR_012918
Software, algorithm	bedtools (2.26.0)	PMID: 20110278	RRID:SCR_006646
Software, algorithm	tophat (2.0.13)	PMID: 23618408	RRID:SCR_013035
Software, algorithm	edgeR (3.14.0)	PMID: 19910308	RRID:SCR_012802
Software, algorithm	UCSC genome browser	PMID: 26590259	RRID:SCR_005780