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. Author manuscript; available in PMC: 2019 Jul 6.
Published in final edited form as: J Mol Biol. 2018 May 18;430(14):2042–2050. doi: 10.1016/j.jmb.2018.05.017

Fig. 4.

Fig. 4.

Effects of single-point mutations in REV1 UBM2 using S. cerevisiae as a model system. (a) Amino acid sequences of human and S. cerevisiae REV1 UBM2 and UBM1 regions. Similar and identical residues are highlighted in blue and yellow, respectively. (b) Frequencies of mutagenesis (top) and cell viability (bottom) following UV irradiation of yeast cells expressing wild-type or mutated REV1. (c) Viability of yeast cells expressing wild-type or mutated REV1 in presence of different concentrations of MMS.