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. Author manuscript; available in PMC: 2018 Oct 17.
Published in final edited form as: Oncogene. 2018 Apr 17;37(28):3879–3893. doi: 10.1038/s41388-018-0239-7

Figure 3. The miR-106b-25 cluster produces an increase in Notch1-ICD stability.

Figure 3

(A–B) Top: Western blot analysis in (A) MCF7 and (B) Sum159 NS and Cluster (CLR) cell lines after treatment with cyclohexamide (CHX - 20μM) for indicated periods of time. Bottom: Quantification of the above representative western blots (n=3), and approximate half-lives (representative data of 3 experiments). The half-lives shown were approximated from the graphs shown from one experiment and are representative of all 3 experiments.