Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of performance characteristics of existing pMSAs and the optimized pMSA for Align-GVGD (C15 cut-off)
| Alignment | Species (n) | Average n substitutions/position | AUC (95% CI) | True Positives | True Negatives | False Positives | False Negatives | MCC |
|---|---|---|---|---|---|---|---|---|
| Human to Frog | 8 | 2.15 | 0.862 (0.786, 0.937) | 219 | 53 | 18 | 28 | 0.605 |
| Human to Zebrafish | 9 | 2.95 | 0.869 (0.795, 0.943) | 219 | 54 | 17 | 28 | 0.616 |
| Optimized pMSA | 11 | 3.70 | 0.907 (0.881, 0.934) | 220 | 54 | 17 | 27 | 0.622 |
