Table 3.
Multivariable models of mortality with GLS adjusted to univariate clinical and imaging predictors (at p≤0.20) for patients with ischemic cardiomyopathy.
| VARIABLES | Univariable | Multivariable Model Using LGE extent | Multivariable Model Using LGE presence | |||
|---|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | |
| Age | 1.025 (1.006-1.044) | 0.008 | 1.022 (1.002-1.043) | 0.031 | 1.022 (1.002-1.041) | 0.029 |
| BMI | 1.011 (1.001-1.022) | 0.038 | 1.001 (0.991-1.012) | 0.787 | 1.002 (0.992-1.012) | 0.732 |
| Diabetes | 1.574 (1.018-2.435) | 0.041 | 1.949 (1.188-3.199) | 0.008 | 1.933 (1.183-3.160) | 0.009 |
| Hyperlipidemia | 1.351 (0.890-1.816) | 0.153 | 0.834 (0.483-1.438) | 0.513 | 0.837 (0.486-1.442) | 0.521 |
| LVEDV index | 1.010 (1.001-1.020) | 0.049 | 1.000 (0.994-1.006) | 0.986 | 1.000 (0.994-1.006) | 0.987 |
| GLS | 1.312 (1.234-1.395) | <0.001 | 1.942 (1.466-2.573) | <0.001 | 1.952 (1.475-2.584) | <0.001 |
| LGE present | 2.142 (1.283-3.001) | <0.001 | - | - | 1.684 (0.228-12.46) | 0.609 |
| LGE extent | 1.017 (1.005-1.029) | 0.042 | 1.005 (0.980-1.030) | 0.720 | - | - |
| LVEF | 0.978 (0.957-0.998) | 0.048 | 1.012 (0.965-1.062) | 0.720 | 1.010 (0.964-1.058) | 0.678 |
BMI=Body Mass Index, GLS=Global Longitudinal Strain, LGE=Late Gadolinium Enhancement, LVEDV =Left Ventricular End Diastolic Volume Index, LVEF=Left Ventricular Ejection Fraction.