Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 12;8:10491. doi: 10.1038/s41598-018-28890-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Comparison of IFN responses between wild type ZL1 and ZL1(V2634M). (a/b) Analysis of type I IFN responses in A549 cells. A549 cells were infected with ZL1 and ZL1(V2634M) virus(MOI = 0.01). Cell lysis were harvested at 0 h, 24 h, 48 h, 72 h, 96 h, 120 h post infection. IFNα/β RNA was detected by q-RT-PCR. Data represent the means of three independent assays; Error bars represent standard deviations from the means. (c) Western blot analysis of ZIKV NS5-induced STAT2 degradation in Vero E6. Vero E6 cells were infected with ZL1 and ZL1(V2634M) virus(MOI = 0.01). Cell pellets harvested at hours 0, 24, 48, 72, 96 h, 120 h post infection were detected by using anti-STAT2 antibody. Numbers indicate relative band intensity (STAT2/Tubulin, S/T) and targeted band for densitometry were indicated by triangle.