Table 3.
MVFMTsat vs. MVFSyMRI | MVFMTsat vs. MVFT1w/T2w | MVFSyMRI vs. MVFT1w/T2w | MVFMTsat (%) | MVFSyMRI (%) | MVFT1w/T2w (%) | ||
---|---|---|---|---|---|---|---|
WM | Genu of corpus callosum | 0.38 [−0.08–0.70] | 0.06 [−0.39–049] | −0.01 [−0.45–0.43] | 42.81 ± 2.01 | 39.36 ± 1.36 | 35.87 ± 3.57 |
Splenium of corpus callosum | 0.40 [−0.05–0.72] | −0.05 [−0.48–0.40] | 0.15 [−0.31–0.56] | 35.49 ± 1.52 | 39.08 ± 1.47 | 33.26 ± 3.50 | |
Anterior limb of internal capsule | 0.67*** [0.45–0.81] | 0.41* [0.11–0.64] | 0.40* [0.10–0.63] | 28.88 ± 1.50 | 33.58 ± 2.08 | 33.70 ± 3.82 | |
Posterior limb of internal capsule | 0.64*** [0.41–0.79] | 0.27 [−0.045–0.54] | 0.24 [−0.081–0.51] | 28.51 ± 1.21 | 33.65 ± 1.83 | 30.67 ± 3.28 | |
Anterior corona radiata | 0.68*** [0.47–0.82] | 0.34* [0.034–0.59] | 0.44** [0.15–0.66] | 36.26 ± 1.42 | 34.56 ± 1.30 | 32.84 ± 3.36 | |
Superior corona radiata | 0.57*** [0.32–0.75] | 0.23 [−0.092–0.50] | 0.37* [0.06–0.61] | 32.39 ± 1.26 | 29.86 ± 1.64 | 28.59 ± 3.06 | |
Posterior corona radiata | 0.54*** [0.27–0.73] | −0.052 [−0.36–0.26] | 0.23 [−0.085–0.51] | 30.55 ± 1.13 | 31.02 ± 1.37 | 28.80 ± 2.98 | |
Posterior thalamic radiation | 0.65*** [0.43–0.80] | 0.10 [−0.22–0.40] | 0.099 [−0.22–0.40] | 31.87 ± 1.48 | 36.18 ± 1.34 | 30.62 ± 3.05 | |
External capsule | 0.66*** [0.43–0.80] | 0.31* [0.001–0.57] | 0.16 [−0.16–0.45] | 27.20 ± 1.17 | 28.95 ± 1.31 | 31.21 ± 3.17 | |
Superior longitudinal fasciculus | 0.47** [0.19–0.68] | 0.20 [−0.12–0.48] | 0.60*** [0.35–0.77] | 33.11 ± 1.30 | 31.36 ± 1.48 | 29.81 ± 3.18 | |
Subcortical GM | Pallidum | 0.72*** [0.53–0.85] | 0.53** [0.26–0.72] | 0.52** [0.24–0.71] | 21.97 ± 1.41 | 22.34 ± 3.22 | 35.29 ± 3.88 |
Thalamus | 0.72*** [0.53–0.84] | 0.41** [0.12–0.64] | 0.50** [0.22–0.70] | 22.60 ± 1.38 | 20.66 ± 2.26 | 27.77 ± 3.00 | |
Cortical GM | Precentral | 0.41** [0.12–0.64] | 0.12 [−0.20–0.42] | 0.53** [0.26–0.72] | 13.27 ± 1.43 | 7.99 ± 1.21 | 19.60 ± 2.19 |
Postcentral | 0.24 [−0.076–0.51] | −0.10 [−0.40–0.22] | 0.59*** [0.34–0.76] | 13.22 ± 1.42 | 8.25 ± 1.19 | 19.38 ± 2.06 | |
Heschl | 0.20 [−0.12–0.48] | 0.098 [−0.22–0.40] | 0.35* [0.041–0.60] | 14.06 ± 1.93 | 7.46 ± 1.51 | 20.05 ± 2.17 | |
Lingual | 0.24 [−0.079–0.51] | 0.25 [−0.069–0.52] | 0.47** [0.18–0.68] | 12.35 ± 1.17 | 7.10 ± 0.85 | 20.27 ± 2.08 |
Data are the Spearman’s ρ correlation coefficients ± 95% confidence intervals or the mean ± standard deviation.
Abbreviations: MVF = myelin volume fraction; MTsat = magnetization transfer saturation; SyMRI = simultaneous tissue relaxometry of R1 and R2 relaxation rates and proton density; T1w/T2w = ratio of T1-weighted to T2-weighted images; WM = white matter; GM = gray matter; ROI = region of interest.
Note: *p < 0.05, **p < 0.01, ***p < 0.001.