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. 2018 Jul 12;8:10503. doi: 10.1038/s41598-018-28963-0

Figure 4.

Figure 4

Migration pattern of MDA-MB-231 daughter cells on the body of a senescent cell. (a) The sequence of snapshot images shows cells undergoing cell-rounding, all of which are newly replicated daughter cells, migrating towards the senescent core (mean radial velocity: 38.7 μm/hr) (see Supplementary Video S2). (b) A sequence of close-up images showing a process of cell division and, the simultaneous mitotic cell-rounding [square-boxed area in (a)‘s first sequence]. (c) A snapshot image of a senescent cell culminated with a small cell cluster (marked by an arrow) attached onto its core. (scale bar: 100 μm).