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. 2018 Jul 6;9:1552. doi: 10.3389/fimmu.2018.01552

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Copyright © 2018 Ohl, Fragoulis, Klemm, Baumeister, Klock, Verjans, Böll, Möllmann, Lehrke, Costa, Denecke, Schippers, Roth, Wagner, Wruck and Tenbrock.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nrf2 activates genes regulating cell cycle and metabolic pathways in myeloid-derived suppressor cells (MDSCs). (A) Gene expression in CD11b⁺Gr-1⁺ cells from Keap^fl/fl and VAV^creKeap^fl/fl mice. Colors indicate significant upregulation (of at least 1.5-fold; red) or downregulation (of at least 1.5-fold; blue). (B) Selection of pathways and associated genes which were significantly enriched.