Table 2.

Systematic analysis of mortality rates between ICH and non-ICH adult ECMO cohorts.

Study	Study design	Patients (n)	% V-A ECMO	Outcome studied	ICH		No ICH		RR	95% CI	p-value
					Non-survivors (n)	Survivors (n)	Non-survivors (n)	Survivors (n)
Aubron et al. 7	Multicenter, retrospective	149	74	Hospital mortality	5	0	48	96	3.00	2.38–3.78	<0.0001
Davies et al. 10	Multicenter, retrospective	68	7	ICU mortality	6	0	14	48	4.43	2.79–7.02	<0.0001
Fletcher-Sandersjöö et al. 23	Single-center, retrospective	253	36	30 day mortality	44	10	52	134	2.91	2.24–3.79	<0.0001
Kasirajan et al. 14	Single-center, retrospective	74	100	ICU mortality	13	1	36	24	1.55	1.20–1.99	0.001
Klinzing et al. 15	Single-center, retrospective	74	27	6 month mortality	7	1	35	31	1.65	1.17–2.33	0.005
Lockie et al. 16	Single-center, retrospective	250	100	ICU mortality	13	28	44	162	1.48	0.88–2.50	0.137
Luyt et al. 19	Single-center, retrospective	135	0	ICU mortality	7	3	46	81	1.93	1.21–3.08	0.006
Omar et al. 20	Single-center, retrospective	154	81	Hospital mortality	10	2	93	49	1.27	0.96–1.68	0.092
Patroniti et al. 25	Multicenter, retrospective	60	2	ICU mortality	1	0	18	41	3.28	2.23–4.82	<0.0001

ECMO, extracorporeal membrane oxygenation; ICH, intracranial hemorrhage; V-A, venoarterial; RR, risk ratio; CI, confidence interval