Table 2. Logistic regression analysis of associations between TNFSF4 gene rs3850641 polymorphism and the risk of myocardial infarction.
| Genotype | Cases1 (n=454) | Controls1 (n=512) | OR (95% CI); P | Adjusted OR2 (95% CI); P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| AG vs. AA | 128/300 | 28.2/66.1 | 135/360 | 26.3/70.3 | 1.14 (0.86,1.52); 0.377 | 1.07 (0.78,1.47);0.665 |
| GG vs. AA | 25/300 | 5.5/66.1 | 15/360 | 2.9/70.3 | 2.00 (1.04,3.86); 0.039 | 2.29 (1.20,4.69);0.023 |
| GG+AG vs. AA | 153/300 | 33.7/66.1 | 150/360 | 29.2/70.3 | 1.22 (0.93,1.61); 0.146 | 1.19 (0.88,1.60);0.264 |
| GG vs. AG+AA | 25/428 | 5.5/94.3 | 15/495 | 2.9/96.6 | 1.93 (1.00,3.70); 0.049 | 2.25 (1.10,4.57);0.026 |
| G vs. A | 178/728 | 19.6/80.2 | 165/855 | 16.1/83.5 | 1.27 (1.00,1.60); 0.047 | |
Bold values are statistically significant (P<0.05).
1
The genotyping was successful in 453 cases and 510 controls.
2
Adjusted for age, sex, smoking, drinking, hypertension, diabetes.