Table 4. Stratified analyses between TNFSF4 rs3850641 polymorphism and the risk of myocardial infarction.
| Variable | TNFSF4 rs3850641 (case/control) | GG vs. AA | GG+AG vs. AA | GG vs. AG+AA | ||
|---|---|---|---|---|---|---|
| GG | AG | AA | ||||
| Sex | ||||||
| Male | 17/8 | 83/89 | 186/235 | 2.68 (1.13,6.36);0.025 | 1.30 (0.93,1.83);0.127 | 2.56 (1.09,6.02);0.031 |
| Female | 8/7 | 45/46 | 114/125 | 1.25 (0.44,3.57);0.672 | 1.10 (0.69,1.73);0.693 | 1.23 (0.44,3.47);0.697 |
| Age | ||||||
| <60 | 12/6 | 51/64 | 139/164 | 2.36 (0.86,6.45);0.094 | 1.06 (0.71,1.60);0.773 | 2.40 (0.88,6.52);0.086 |
| ≥60 | 13/9 | 77/71 | 161/196 | 1.76 (0.73,4.22);0.206 | 1.37 (0.95,1.98);0.092 | 1.62 (0.68,3.86);0.276 |
| Smoking status | ||||||
| Nonsmoker | 14/14 | 47/92 | 122/251 | 2.06 (0.95,4.45);0.067 | 1.18 (0.81,1.74);0.386 | 2.03 (0.95,4.35);0.069 |
| Smoke | 11/1 | 81/43 | 178/109 | 6.74 (0.86,52.90);0.070 | 1.28 (0.83,1.97);0.621 | 6.46 (0.83,50.49);0.076 |
| Drinking status | ||||||
| No | 15/14 | 99/105 | 214/315 | 1.39 (1.00,1.92);0.233 | 1.41 (1.03,1.92);0.030 | 1.44 (0.68,3.02);0.338 |
| Yes | 10/1 | 29/30 | 86/45 | 5.23 (0.65,42.18);0.120 | 0.66 (0.36,1.19);0.168 | 6.52 (0.82,52.00);0.070 |
| Hypertension | ||||||
| No | 10/7 | 50/85 | 125/207 | 0.97 (0.64,1.47);0.974 | 1.08 (0.73,1.60);0.702 | 2.38 (0.89,6.38);0.084 |
| Yes | 15/8 | 78/50 | 175/173 | 2.37 (0.88,6.37);0.089 | 1.40 (0.95,2.08);0.092 | 1.50 (0.63,3.62);0.362 |
| Diabetes | ||||||
| No | 18/11 | 81/114 | 195/308 | 2.59 (1.20,5.59);0.016 | 1.25(0.91,1.72);0.169 | 2.50 (1.16,5.38);0.019 |
| Yes | 7/4 | 47/21 | 105/52 | 0.87 (0.24,3.09);0.826 | 1.07 (0.60,1.91);0.820 | 0.84 (0.24,2.96);0.797 |
Bold values are statistically significant (P<0.05).