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. 2018 Jun 6;5(7):815–831. doi: 10.1002/acn3.577

Table 4.

Multinomial logistic regression models (control for age/gender)

Aβ pathology group 1 vs Aβ pathology group 2 Aβ pathology group 1 vs Aβ pathology group 3 Aβ pathology group 2 vs Aβ pathology group 3
P‐value odds ratio 95% confidence interval P‐value odds ratio 95% confidence interval P‐value odds ratio 95% confidence interval
CAA severity 0.583 0.520 0.050–5.376 0.016 0.060 0.006–0.597 0.001 0.031 0.004–0.240
CAA stage 0.535 0.543 0.079–3.734 0.014 0.072 0.009–0.588 0.002 0.133 0.037–0.481
CAA type 1 0.452 2.812 0.190–41.587 0.689 1.729 0.119–25.179 0.035 4.861 1.115–21.183
CAA type 2 0.249 4.385 0.355–54.137 0.040 12.106 1.123–130.467 0.162 2.761 0.665–11.452
APOE ε4 allele 0.998 2.678 × 10‐9 ‐ 0.998 1.176 × 10‐8 ‐ 0.021 0.228 0.064–0.804
Arterial hypertension 0.010 0.028 0.002–0.426 0.042 0.080 0.007–0.918 0.160 2.898 0.657–12.788
Diabetes mellitus 0.282 0.272 0.025–2.914 0.726 0.687 0.084–5.606 0.207 2.530 0.597–10.713
Alcohol abuse 1.000 1.398 ‐ 1.000 1.172 x 10‐8 ‐ 0.998 2.279 × 10‐8 ‐
Aβ‐MTL phase 0.008 5.279 1.530–18.210 0.042 2.867 1.039–7.907 0.134 1.841 0.829–4.089
Braak‐NFT stage 0.037 3.008 1.069–8.466 0.137 2.095 0.790–5.555 0.131 1.436 0.897–2.298
CERAD score 0.034 3.322 1.092–10.103 0.433 1.517 0.535–4.296 0.021 2.190 1.128–4.253
Aβ plaque load 0.048 1.328 1.002–1.759 0.124 1.222 0.947–1.577 0.303 1.087 0.928–1.273
Aβ N3pE plaque load 0.009 2.613 1.271–5.374 0.057 1.816 0.982–3.357 0.106 1.439 0.926–2.237
Aβ pS8 plaque load 0.000 2.514 × 10 77 1.034 × 10 77–6.112 × 10 77 ‐ ‐ ‐ 0.099 2.110 0.868–5.128
CDR score 0.000 3.733 × 10 10 2.096 × 10 10 –6.650 × 10 10 0.997 6.324 × 10‐13 ‐ 0.389 1.289 0.724–2.296

Aβ = amyloid β, APOE = apolipoprotein E, CAA = cerebral amyloid angiopathy, CDR = clinical dementia rating, CERAD = Consortium to Establish a Registry for Alzheimer's disease, MTL = medial temporal lobe, NFT = neurofibrillary tangle; Aβ/Aβ N3pE/Aβ pS8 plaque load,9 Aβ‐MTL phase,27 Braak‐NFT stage,25 CAA severity,29 CAA stage,30 CAA type,31 CDR score,32 CERAD score.26 Bold values represent statistically significant results.