Table 1.
Characteristics of Study Cohort (n = 20,197)
| AD Cases | Controls | ||||
|---|---|---|---|---|---|
| WHICAP | ADSP | WHICAP | ADSP | External | |
| N | 1371 | 5594 | 2331 | 4506 | 6395 |
| Combined | 6965 | 13,232 | |||
| Age (mean ± SD) | 81.4 ± 6.2 | 75.4 ± 8.4 | 78.1 ± 6.8 | 86.07 ± 4.53 | N/A |
| Combined | 76.7 ± 8.5 | 83.4 ± 6.7 | N/A | ||
| Sex (%F) | 68.5 | 57.2 | 67.6 | 41.1 | 47.3 |
| Combined | 59.4 | 45.2 | |||
| APOE E4 (% Carrier) | 28.37 | 42.40 | 26.30 | 15.14 | N/A |
| Combined | 39.64 | 18.94 | N/A | ||
Mean age and APOE E4 carrier % do not include the External controls; Age for cases indicates age at diagnosis, and for controls the age at last assessment or age when last known to be free of dementia.