Figure EV6. Relative count of arc‐, slit‐, and ring‐shaped oligomers over time.
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A–CThe numbers of arc‐, slit‐, and ring‐shaped oligomers were determined from time‐lapse AFM topographs recording the GSDMDNterm oligomerization and pore formation (Fig 4 and Appendix Fig S3 and S4). The number of arc‐, slit‐, and ring‐like oligomers was normalized to 1. The total number of GSDMD oligomers analyzed was 1,398 in (A), 1,142 in (B), and in 178 (C).