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. 2018 Jun 6;52(2):121–128. doi: 10.2478/raon-2018-0023

Table 1.

Recommendations for target definition according to EORTC, RTOG and ESTRO-ACROP

Contouring approach Dose prescription GTV CTV
EORTC single phase 30 × 2.0 Gy Resection cavity + residual T1 enhancement GTV + 2 cm
RTOG two phases 23 × 2.0 Gy GTV1: Resection cavity + residual T1 enhancement + FLAIR abnormality (oedema) CTV1 = GTV1 + 2 cm (the margin is 2.5 cm in cases where no oedema is presented)
+ 7 × 2.0 Gy GTV2: Resection cavity + residual T1 enhancement GTV2 + 2 cm
ESTRO-ACROP 30 × 2.0 Gy Resection cavity + residual T1 enhancement + FLAIR abnormality (oedema) for secondary glioblasomas GTV + 2 cm

Abbreviations: EORTC = European Organisation for Research and Treatment of Cancer; ESTRO-ACROP = European Society for Radiotherapy & Oncology - Advisory Committee on Radiation Oncology Practice; CTV = clinical target volume; FLAIR = Fluid-attenuated Inversion Recovery. GTV = gross tumor volume; RTOG = Radiation Therapy Oncology Group