Table 1.
Patients and tumour characteristics, concomitant diseases
| All N = 175 (100%) | Left BC group N = 84 (48%) | Right BC group N = 91 (52%) | p value | ||
|---|---|---|---|---|---|
| Age in years (Median [Q1–Q3]) | 58 (49–64) | 59 (52–67) | 55 (46–63) | 0.0096 | |
| Menopause status | Premenopause | 90 (51.4%) | 38 (45.2%) | 52 (57.1%) | 0.155 |
| Pomenopause | 85 (48.5%) | 46 (54.8%) | 39 (42.9%) | ||
| Histological type | Ductal invasive | 168 (96%) | 81 (96.4%) | 87 (95.6%) | 1 |
| Lobular invasive | 4 (2.3%) | 2 (2.4%) | 2 (2.2%) | ||
| Other | 3 (1.7%) | 1 (1.2%) | 2 (2.2%) | ||
| Histo-pathological grade | G 1 | 2 (1.1%) | 0 | 2 (2.2%) | 0.337 |
| G 2 | 48 (27.4%) | 21 (25%) | 27 (29.7%) | ||
| G 3 | 125 (71.5%) | 63 (75%) | 62 (68.1%) | ||
| Hormonal receptors | ER positive | 97 (55.4%) | 53 (63%) | 44 (48.3%) | 0.851 |
| PR positive | 82 (46.8%) | 43 (51.2%) | 39 (42.8%) | ||
| ER in PR negative | 73 (41.7%) | 28 (33.3%) | 45 (49.4%) | ||
| Concomitant disease | Smoking | 33 (19%) | 13 (15%) | 20 (22%) | 0.365 |
| Arterial hypertension | 35 (20%) | 21 (25%) | 14 (15.4%) | 0.161 | |
| Diabetes | 3 (1.7%) | 3 (3.4%) | 0 | 0.108 | |
| Hyperlipidemia | 30 (17.1%) | 16 (19%) | 14 (15.4%) | 0,658 | |
| Known heart disease* | 4 (2.3%) | 1 (1.2%) | 3 (3.3%) | 0.621 |
BC = breast cancer; ER = estrogens receptor; PR = progesterone receptor; Q1–Q3 = quartiles
*
All diseases had been already present at diagnosis of breast cancer. Group 1: mild aortic stenosis; Group 2: mitral valve prolapse; compensated hypertonic heart and symptomatic angina pectoris; undefined cardiomyopathy