Table 1.
Baseline demographics and characteristics (ITT population)
| Parameter | Lotilaner (n = 112) |
Fipronil (n = 57) |
Z-value/ χ2-valuea |
P-value | |
|---|---|---|---|---|---|
| Age (years) | Arithmetic mean ± SD | 4.15 ± 3.38 | 4.42 ± 3.64 | Z = 0.29 | 0.7704 |
| Minimum–Maximum | 0.20–17.0 | 0.50–14.0 | |||
| Sex | Male | 60 (54%) | 33 (58%) | Z = 0.53 | 0.6266 |
| Female | 52 (46%) | 24 (42%) | |||
| Body weight (kg) | Arithmetic mean ± SD | 4.1 ± 1.1 | 4.1 ± 1.0 | Z = 0.55 | 0.5854 |
| Minimum–Maximum | 1.5–7.4 | 1.5–5.8 | |||
| Breed | Purebred | 21 (19%) | 10 (18%) | χ2 = 0.66, df = 4 | 0.9562 |
| Crossbred | 91 (81%) | 47 (82%) | |||
| Hair length | Short | 81 (72%) | 41 (72%) | Z = 0.36 | 0.7208 |
| Medium | 13 (12%) | 13 (23%) | |||
| Long | 18 (16%) | 3 (5%) | |||
| Husbandry | Countryside | 84 (75%) | 42 (74%) | Z = 0.18 | 1.0000 |
| Urban | 28 (25%) | 15 (26%) | |||
| Time spent | Mostly indoors | 19 (17%) | 5 (9%) | Z = 1.44 | 0.1697 |
| Mostly outdoors | 93 (83%) | 52 (91%) | |||
| Day 0 tick count (live attached) | Number | 454 | 215 | Z = 0.07 | 0.9411 |
| Geometric mean | 3.60 | 3.52 | – | – |
Abbreviations: n, number of primary cats; SD, standard deviation
aZ of a Mann-Whitney test; χ2 of a Kruskal-Wallis test (of treatment vs breed)