Table 2.

ANCOVA analysis for non-inferiority testing - live attached tick counts (PP)

Day	Lotilaner (n = 112)			Fipronil (n = 57)			Comparison		95% CI
	Geometric mean tick count	Est	SE	Geometric mean tick count	Est	SE	t-value	P-valuea
0	3.60	na	na	3.52	na	na	–	–	–
7	0.00	0.00	0.01	0.01	0.01	0.01	t(162) = 1.32	0.1876	0.97–1.01
14	0.00	0.00	0.01	0.04	0.05	0.02	t(164) = 2.08	0.0394	0.92–1.00
21	0.00	0.01	0.02	0.09	0.10	0.03	t(164) = 2.82	0.0054	086–0.97
28	0.06	0.06	0.04	0.37	0.35	0.07	t(162) = 4.04	< 0.0001	0.69–0.88
42	0.00	0.00	0.03	0.22	0.22	0.04	t(163) = 4.53	< 0.0001	0.75–0.89
56	0.04	0.03	0.03	0.22	0.21	0.05	t(162) = 3.25	0.0014	0.78–0.94
70	0.01	0.01	0.02	0.11	0.10	0.03	t(160) = 2.42	0.0167	0.85–0.98
84	0.00	0.00	0.01	0.01	0.01	0.01	t(159) = 1.36	0.1747	0.97–1.01
Mean	0.01	0.02	0.02	0.13	0.18	0.03	t(164) = 5.16	< 0.0001	0.82–0.91

Abbreviations: Est, estimate; na, not applicable; SE, standard error

^aSignificant values (P < 0.05) in bold