Table 3.
Ten CpG islands showing the strongest evidence for hypomethylation in NAFLD cirrhosis
| CGI location | Gene ID | Δ Beta | P value | FDR |
|---|---|---|---|---|
| chr11: 63753414-63754454 | OTUB1 | − 0.14 | 1.24E−10 | 2.69E−08 |
| chr1: 155947678-155948490 | ARHGEF2 | − 0.17 | 1.79E−07 | 1.09E−05 |
| chr15: 60689749-60690430 | ANXA2 | − 0.15 | 4.05E−07 | 1.63E−05 |
| chr8: 59571603-59572526 | NSMAF | − 0.18 | 5.93E−07 | 1.63E−05 |
| chr2: 233925091-233925318 | INPP5D | − 0.11 | 7.39E−07 | 1.63E−05 |
| chr7: 106508057-106508733 | PIK3CG | − 0.14 | 8.91E−07 | 1.63E−05 |
| chr9: 123690771-123691675 | TRAF1 | − 0.16 | 1.09E−06 | 1.63E−05 |
| chr15: 72522131-72524238 | PKM2 | − 0.17 | 8.35E−06 | 4.44E−05 |
| chr21: 32929927-32932017 | TIAM1 | − 0.17 | 1.32E−05 | 5.70E−05 |
| chr11: 128391712-128392611 | ETS1 | − 0.17 | 1.93E−05 | 7.38E−05 |