Table 1.
Patient characteristics and clinical manifestations at diagnosis of different age groups
| Characteristics | 0–2 y | 3–9 y | 10–16 y | P value |
|---|---|---|---|---|
| Number (%) | 34 (23.8) | 46 (32.2) | 63 (44.0) | |
| Male sex, n (%) | 24 (70.6) | 28 (60.9) | 37 (58.7) | 0.50 |
| Diagnosis CD, n (%) | 30 (88.2) | 31 (67.4) | 52 (82.5) | 0.05 |
| Genetics disease, n (%) | 13 (38.2) | 1 (2.2) | 0 (0.0) | < 0.01 |
| Family history of IBD, n (%) | 5 (14.7) | 1 (2.2) | 0 (0.0) | < 0.01 |
| Median time from symptom onset to diagnosis, mo (IQR) | 5 (9.3) | 4 (10.3) | 4.5 (8.0) | 0.41 |
| Median duration of follow-up period, mo (IQR) | 9 (22.3) | 38 (45.0) | 31 (46.0) | < 0.01 |
| Symptoms n (%) | ||||
| Abdominal pain | N/Aa | 35 (76.1) | 49 (77.8) | 0.84 |
| Diarrhoea | 32 (94.1) | 36 (78.3) | 38 (60.3) | < 0.01 |
| Blood in stool | 26 (76.5) | 30 (65.2) | 30 (47.6) | 0.02 |
| Oral ulcer | 7 (20.6) | 5 (10.9) | 13 (20.6) | 0.36 |
| Fever | 25 (73.5) | 21 (45.7) | 21 (33.3) | < 0.01 |
| Anaemia | 26 (76.5) | 30 (65.2) | 41 (65.1) | 0.47 |
| weight < -2SD | 16 (47.1) | 8 (17.4) | 10 (15.9) | < 0.01 |
| Growth impairment | 19 (55.9) | 18 (39.1) | 13 (20.6) | < 0.01 |
| limitation of activities | 17 (50) | 13 (28.3) | 14 (22.2) | < 0.01 |
| Joints | 0 (0) | 5 (10.9) | 1 (1.6) | 0.02 |
| Skin | 2 (5.9) | 1 (2.2) | 1 (1.6) | 0.50 |
aAs the presence of abdominal pain in younger children is very difficult to identify, we did not calculate the numbers of 0–2 y group and only compared the other two groups