Table 6.

Univariable and multivariable analyses of clinical variables influencing relapse in CD

Variables	Univariable analysis			Multivariable analysis (significant in univariate)
	HR	95% CI	P value	HR	95% CI	P value
Age
3–9 y vs 0–2 y	0.25	0.14–0.48	< 0.01	0.26	0.13–0.53	< 0.01
10–16 y vs 0–2 y	0.20	0.11–0.36	< 0.01	0.23	0.12–0.44	< 0.01
Sex
female vs male	0.84	0.52–1.36	0.47
Disease location
L2 vs L1	2.18	0.98–4.84	0.06
L3 vs L1	1.29	0.61–2.77	0.51
L4 vs no L4	0.89	0.54–1.46	0.64
Perianal disease, yes vs no	1.59	1.00–2.53	0.048	1.13	0.68–1.88	0.63
Behaviour B2 vs not	1.04	0.66–1.64	0.87
Behaviour B3 vs not	2.08	1.15–3.77	0.02	1.96	1.01–3.81	0.046
Weight < -2SD vs not	1.71	1.04–2.82	0.04	0.96	0.54–1.69	0.88
Growth impairment vs not	1.31	0. 83–2.09	0.25
Top-down treatment vs not	0.69	0.40–1.21	0.20
Steroid dependency vs not	2.26	1.40–3.64	< 0.01	1.88	1.16–3.06	0.01