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. 2018 Jul 13;11:413. doi: 10.1186/s13071-018-2968-4

Table 8.

Geometric (arithmetic) mean counts of live, female I. ricinus ticks and % efficacy of lotilaner, 24 hours after post-treatment infestations

Daya Time-point Untreated control Lotilaner Comparison
Mean Range Mean Range Efficacy (%) t-value P-value
7 Pre-incubation 16.94 (17.50) 9–24 0 (0) 0–0 100 (100) t(7) = 29.5 < 0.0001
Post-incubation 16.94 (17.50) 9–24 0 (0) 0–0 100 (100) t(7) = 29.5 < 0.0001
14 Pre-incubation 13.96 (15.25) 6–27 0 (0) 0–0 100 (100) t(7) = 17.3 < 0.0001
Post-incubation. 13.89 (15.13) 6–26 0 (0) 0–0 100 (100) t(7) = 17.5 < 0.0001
21 Pre-incubation 15.93 (17.63) 5–29 0 (0) 0–0 100 (100) t(7) = 15.8 < 0.0001
Post-incubation. 15.93 (17.63) 5–29 0 (0) 0–0 100 (100) t(7) = 15.8 < 0.0001
28 Pre-incubation 13.00 (13.50) 9–20 0.15 (0.25) 0–2 98.9 (98.1) t(7) = 14.8 < 0.0001
Post-incubation. 13.00 (13.50) 9–20 0.09 (0.35) 0–0 99.1 (99.3) t(7) = 19.4 < 0.0001
35 Pre-incubation 12.85 (13.88) 6–24 0 (0) 0–0 100 (100) t(7) = 18.1 < 0.0001
Post-incubation 12.76 (13.75) 6-24 0 (0) 0–0 100 (100) t(7) = 18.4 < 0.0001

aDay of challenge