Table 1.
Socio-demographic characteristics of patients according to years of starting cART or year of last observation
| Overall N = 8023 |
2002–2006 N = 1543 |
2007–2011 N = 2166 |
2012–2016 N = 4314 |
p | |
|---|---|---|---|---|---|
| Gender, n (%) | |||||
| Female | 1434 (17.9%) | 453 (29.4%) | 368 (17.0%) | 613 (14.2%) | < 0.001 |
| Male | 6589 (82.1%) | 1090 (70.6%) | 1798 (83.0%) | 3701 (85.8%) | |
| Age at first positive anti-HIV test, n (%) | |||||
| < 30 | 2582 (32.2%) | 682 (44.2%) | 637 (29.5%) | 1263 (29.3%) | < 0.001 |
| 30–40 | 2646 (33.0%) | 521 (33.8%) | 742 (34.4%) | 1383 (32.1%) | |
| 40–50 | 1709 (21.3%) | 221 (14.3%) | 475 (22.0%) | 1013 (23.5%) | |
| > 50 | 1079 (13.5%) | 119 (7.7%) | 305 (14.1%) | 655 (15.2%) | |
| Mode of HIV transmission, n (%) | |||||
| HS | 2773 (34.6%) | 590 (38.2%) | 816 (37.7%) | 1367 (31.7%) | < 0.001 |
| PWID | 1131 (14.1%) | 509 (33.0%) | 265 (12.2%) | 357 (8.3%) | |
| MSM | 3528 (44.0%) | 342 (22.2%) | 942 (43.5%) | 2244 (52.0%) | |
| other/unknown | 591 (7.4%) | 102 (6.6%) | 143 (6.6%) | 346 (8.0%) | |
| Education | |||||
| Elementary school | 362 (4.5%) | 162 (10.5%) | 99 (4.6%) | 101 (2.3%) | < 0.001 |
| Junior high school | 1803 (22.5%) | 596 (38.6%) | 528 (24.4%) | 679 (15.7%) | |
| High school | 2576 (32.1%) | 423 (27.4%) | 708 (32.7%) | 1445 (33.5%) | |
| University | 920 (11.5%) | 101 (6.6%) | 217 (10.0%) | 602 (14.0%) | |
| Missing data | 2362 (29.4%) | 261 (16.9%) | 614 (28.4%) | 1487 (34.5%) | |
| Employement | |||||
| Full time worker | 3575 (44.6%) | 703 (45.6%) | 1100 (50.8%) | 1772 (41.1%) | < 0.001 |
| Unemployed | 910 (11.3%) | 307 (19.9%) | 217 (10.0%) | 386 (9.0%) | |
| Self employed | 1231 (15.3%) | 265 (17.2%) | 304 (14.0%) | 662 (15.4%) | |
| Temporary employed | 192 (2.4%) | 75 (4.9%) | 45 (2.1%) | 72 (1.7%) | |
| Student | 296 (3.7%) | 29 (1.9%) | 75 (3.5%) | 192 (4.5%) | |
| Retired | 256 (3.2%) | 40 (2.6%) | 96 (4.4%) | 120 (2.8%) | |
| Housewife | 233 (2.9%) | 103 (6.7%) | 72 (3.3%) | 58 (1.3%) | |
| Other/unknown | 204 (2.5%) | 18 (1.2%) | 40 (1.9%) | 146 (3.4%) | |
| Missing data | 1126 (14.0%) | 3 (0.2%) | 217 (10.0%) | 906 (21.0%) | |
| Residency area | |||||
| Northern Italy | 4540 (56.6%) | 763 (49.5%) | 1226 (56.6%) | 2551 (59.1%) | < 0.001 |
| Central Italy | 2678 (33.4%) | 517 (33.5%) | 769 (35.5%) | 1392 (32.3%) | |
| Southern Italy | 805 (10.0%) | 263 (17.0%) | 171 (7.9%) | 371 (8.6%) | |
| Smokers | |||||
| No | 3589 (44.7% | 532 (34.5%) | 1040 (48.0%) | 2017 (46.8%) | < 0.001 |
| Yes | 3636 (45.3%) | 787 (51.0%) | 990 (45.7%) | 1859 (43.1%) | |
| Not known | 798 (10.0%) | 224 (14.5%) | 136 (6.3%) | 438 (10.2%) | |
| CDC stage | |||||
| C | 714 (8.9%) | 199 (12.9%) | 219 (10.1%) | 296 (6.9%) | < 0.001 |
| A/B | 7309 (91.1%) | 1344 (87.1%) | 1947 (89.9%) | 4018 (93.1%) | |
| Pre treatment CD4 cell/mmc | |||||
| < =200 | 1630 (20.3%) | 404 (26.2%) | 508 (23.5%) | 718 (16.6%) | < 0.001 |
| 201–350 | 1952 (24.3%) | 516 (33.4%) | 699 (32.3%) | 737 (17.1%) | |
| 351–500 | 1761 (22.0%) | 251 (16.3%) | 473 (21.8%) | 1037 (24.0%) | |
| 500-max | 1913 (23.8%) | 308 (20.0%) | 291 (13.4%) | 1314 (30.5%) | |
| Missing data | 767 (9.6%) | 64 (4.2%) | 195 (9.0%) | 508 (11.8%) | |
| Pre treatment log10 HIV RNA | |||||
| < 4 | 1844 (23.0%) | 385 (25.0%) | 427 (19.7%) | 1032 (23.9%) | 0.012 |
| 4–4.7 | 1961 (24.4%) | 379 (24.6%) | 524 (24.2%) | 1058 (24.5%) | |
| 4.8–5.2 | 1644 (20.5%) | 363 (23.5%) | 478 (22.1%) | 803 (18.6%) | |
| 5.2+ | 1590 (19.8%) | 316 (20.5%) | 488 (22.5%) | 786 (18.2%) | |
| Missing data | 984 (12.3%) | 100 (6.5%) | 249 (11.5%) | 635 (14.7%) | |
| Pregnancy status | |||||
| Not pregnant | 7715 (96.2%) | 1517 (98.3%) | 2109 (97.4%) | 4089 (94.8%) | < 0.001 |
| Pregnant | 30 (0.4%) | 5 (0.3%) | 7 (0.3%) | 18 (0.4%) | |
| Missing data | 278 (3.5%) | 21 (1.4%) | 50 (2.3%) | 207 (4.8%) | |