Table 2. Population doubling time of AT-MSCs at various time points in physiologic saline and DMEM.
| Time points | Population doubling time (hours) | ||||||
|---|---|---|---|---|---|---|---|
| Physiologic saline | DMEM | ||||||
| Mean | SD | P | Mean | SD | P | ||
| Initial | 26.59 | 4.70 | – | 30.26 | 4.88 | – | |
| 3 hours | 35.22 | 16.19 | 0.39 | 24.75 | 3.88 | 0.08 | |
| 6 hours | 24.85 | 2.29 | 0.77 | 46.70 | 27.69 | 1.00 | |
| 24 hours | 46.93 | 7.97 | 0.04 | 48.75 | 8.33 | 0.02 | |
| 48 hours | 47.05 | 12.14 | 0.14 | 207.81 | 100.38 | 0.02 | |
| 72 hours | 69.45 | 6.53 | 0.06 | NA | NA | NA | |
| 96 hours | 248.22 | 16.20 | 0.02 | NA | NA | NA | |
SD, standard deviation; P, level of significance compared to initial population doubling time; NA, not applicable due to no proliferation capacity; AT-MCSs, adipose tissue derived mesenchymal stem cells.