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Residues photolabeled by AziISO within α1β3 and α1β3γ2L GABAA receptors within the ECD and/or TMD as well as associated TMD helices M1–M4
| Receptor/subunit | ECD | TMD |
|||
|---|---|---|---|---|---|
| M1 | M2 | M3 | M4 | ||
| α1β3 | |||||
| α | N103 | I239, T230a, L240 | I271, V252, S272 | — | — |
| β | A45 | — | T266 | V290 | — |
| α1β3γ2L | |||||
| α | E250 | P278a, S276a | — | — | |
| β | — | I222, Q224, Y226 | I255, I264 | — | — |
| γ | — | Y241 | — | — | |
ECD, extracellular domain; TMD, transmembrane domain. aResidues near or linking TMD helices.
