Table 3.
Association of CTC counts with metabolic, inflammatory, and tumor markers
| Spearman correlation | P* | |
|---|---|---|
| CA15-3, pg/mL | .40 | .0001 |
| CEA, µg/mL | .31 | .002 |
| CA125, U/mL | .15 | .14 |
| hs-CRP, mg/L | .22 | .02 |
| TNF-α, pg/mL | .18 | .06 |
| VEGF, pg/mL | .13 | .18 |
| PAI-1, ng/mL | .31 | .001 |
| IL-6, pg/mL | .25 | .01 |
| IL-8, pg/mL | .38 | .0001 |
| BMI, kg/m2 | –.23 | .02 |
| Glucose, mmol/L | –.08 | .41 |
| Insulin, pmol/L | –.17 | .08 |
| HOMA | –.17 | .08 |
| Leptin, ng/mL | –.26 | .01 |
| Leptin:adiponectin ratio | –.26 | .01 |
| Adiponectin, µg/mL | .10 | .32 |
| Albumin, g/L | –.14 | .178 |
| Creatinine kinase, U/L | .13 | .194 |
| Free fatty acids, mmol/L | .29 | .004 |
*
P value from testing the hypothesis that the Spearman rank correlation is zero. BMI = body mass index; CA15-3 = cancer antigen 15-3; CEA = carcinoembryonic antigen; CRP = C-reactive protein; CTC = circulating tumor cell; HOMA = homeostasis model assessment; IL = interleukin; PAI-1 = plasminogen activator inhibitor 1; TNF = tumor necrosis factor; VEGF = vascular endothelial growth factor.