Table 2.
Clinical characteristics and lung function measurements of COPD patients with paired MBW assessments
| Clinical parameter | COPD (n=17) | p-value |
|---|---|---|
| FRC (L) | ||
| FRCN2 | 4.24 (1.47) | |
| FRCSF6 | 3.49 (1.00) | 0.002 |
| FRC (%) predicted | ||
| FRCN2 | 136.8 (42.8) | 0.002 |
| FRCSF6 | 112.4 (28.0) | |
| Lung clearance index | ||
| LCIN2 | 12.3 (2.2) | |
| LCISF6 | 11.9 (3.1) | 0.4 |
| FEV1(%) | 64.2 (21.1) | |
| FVC (%) | 101.4 (13.6) | |
| FEV1/FVC | 0.5 (0.1) |
Note: Parametric data are expressed as mean and SD, and comparisons were performed using Student’s t-test.
Abbreviations: FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FRC, functional residual capacity; FRCN2, FRC measured by nitrogen washout; FRCSF6, FRC measured by sulphur hexafluoride washout; LCIN2, lung clearance index measured by nitrogen washout; LCISF6, lung clearance index measured by sulphur hexafluoride washout; MBW, multiple-breath washout.