Table 1. miRNA differentially expressed in recurrent high-grade glioma.

miRNA	Fold change	p-value	Select predicted targets (mirdb)
hsa-mir-210	1.91	0.003	IGF2, FGFRL1, AIFM3, CEND1
hsa-mir-191	1.44	0.005	TMOD2 (neuronal), MAPK9, CRCAM, CDK6, Notch2, DAPK1, TRAF3, BDNF
hsa-mir-101	1.66	0.005	TGFBR1, GLTSCR1
hsa-mir-126*	0.44	0.016	MACC1, MAP3K2, TNFAIP8L3, RASAL2, CCNT2, MAPK10, TRAF6
hsa-mir-96	0.33	0.018	MTSS1, SDC2, NEUROD4, MAP2K1, RAB35
hsa-mir-146b	1.55	0.024	ITPR2, RGS4, IL1A, NAV3, NOVA1, SRSF6
hsa-mir-25	0.72	0.024	CD69, JMY, RAB23, MYO1B, MAP2K4
hsa-mir-24	1.41	0.031	CALCR, AAK1, KSR2
hsa-mir-20a	0.69	0.034	MAP3K2, PDCD1LG2, AAK1, TNFRSF21, NEDD4L

Fold change represents the mean expression value of recurrent glioma divided by initial tumor. P-value calculated using a paired Student’s T-test.