Table 2. Select differentially-expressed genes in recurrent GBM.

Upregulated in recurrence
Gene name	Gene symbol	Relative expression	P-value
transferrin	TF	5.34	0.0085
interferon-induced protein with tetratricopeptide repeats 2	IFIT2	3.54	0.0006
apoptosis-associated tyrosine kinase	AATK	3.38	0.0125
cyclin-dependent kinase 18	CDK18	3.30	0.0292
breast carcinoma amplified sequence 1	BCAS1	2.94	0.0221
microtubule-associated protein 7	MAP7	2.59	0.0101
fibroblast growth factor receptor 2	FGFR2	2.42	0.0400
ferritin, light polypeptide	FTL	2.35	0.0025
fibroblast growth factor 1	FGF1	2.22	0.0058
signal transducer and activator of transcription 1	STAT1	2.08	0.0019
lysosomal-associated membrane protein 2	LAMP2	1.78	0.0008

Downregulated in recurrence
Gene name	Gene symbol	Relative expression	P-value
neurocan	NCAN	0.26	0.0433
glutamate receptor, ionotropic, AMPA 2	GRIA2	0.45	0.0334
fatty acid binding protein 7, brain	FABP7	0.48	0.0236
ets variant 1	ETV1	0.49	0.0209
nestin	NES	0.52	0.0370
TNF receptor-associated factor 4	TRAF4	0.53	0.0334
melanoma antigen family D, 4	MAGED4	0.54	0.0076
neuro-oncological ventral antigen 1	NOVA1	0.55	0.0330

P-values calculated using a two-sided Student’s T-Test