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. 2018 Feb 22;99(1):196–211. doi: 10.1093/biolre/ioy049

Table 2.

Regulatory sequences demonstrated to drive Cre expression in mouse trophoblast cell lineages.

Regulatory sequencea Cellular target(s) References
Cyp19a1 All trophoblast lineages first detectable in extraembryonic ectoderm and ectoplacental cone structures 146
Chimeric Tpbpa/Ada enhancer All trophoblast lineages 151
Krt5 All trophoblast lineages first detectable in the ectoplacental cone; visceral yolk sac 152
Tpbpa Trophoblast progenitors in the ectoplacental cone that give rise to subsets of trophoblast giant cells, spongiotrophoblast, glycogen trophoblast cells 148
Prdm1 Trophoblast progenitors in the junctional zone, spongiotrophoblast, subsets of trophoblast giant cells, and glycogen trophoblast cells 149
Prl3d1 Trophoblast giant cells 150
Prl2c2 Trophoblast giant cells 150
Prl3b1 Placenta (specific cell types were not reported; would expect trophoblast giant cell expression) 153
Ctsq Trophoblast giant cells of the labyrinth zone and lining channels in the junctional zone 155
Gcm1 Syncytiotrophoblast layer-II 147, 154

aAll regulatory sequences are from the mouse except for human Cyp19a1.