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. Author manuscript; available in PMC: 2019 May 15.
Published in final edited form as: Neuropharmacology. 2017 Oct 28;134(Pt B):259–271. doi: 10.1016/j.neuropharm.2017.10.034

Figure 1.

Figure 1

The DCE-MRI method consists of five steps. During data acquisition we choose the contrast agent (CA) type and dosage and the MRI sequence for T1 mapping. T1 and CA concentrations are then calculated from the data. Next we have to make a choice of the tracer-kinetic model to use. Patlak model is one such example. The model parameters are finally calculated.