Table 4.
Cox Regression Model for HRs for Deaths From Amyotrophic Lateral Sclerosis in the Women’s Health Initiativea
| Variable | HR (95% CI) | P Value |
|---|---|---|
| Age | 1.05 (1.02-1.07) | <.001 |
| BMI | 0.98 (0.95-1.01) | .14 |
| Race/ethnicity | ||
| Black | 1.22 (0.66-2.25) | .10 |
| Other | 0.31 (0.10-0.97) | |
| White | 1 [Reference] | |
| Region | ||
| Midwest | 0.93 (0.58-1.50) | .95 |
| Northeast | 1.06 (0.68-1.66) | |
| South | 0.96 (0.60-1.52) | |
| West | 1 [Reference] | |
| Smoking status | ||
| Current | 1.68 (0.92-3.06) | .22 |
| Past | 1.02 (0.72-1.44) | |
| Never | 1 [Reference] | |
| Education | ||
| High school or less | 1 [Reference] | .93 |
| College graduate or higher | 0.94 (0.60-1.46) | |
| Some college | 0.91 (0.58-1.43) | |
| Duration of strenuous PA per episode, mina | ||
| None | 1 [Reference] | .11 |
| <20 | 1.36 (0.63-2.92) | |
| 20-39 | 0.86 (0.45-1.65) | |
| ≥40 | 1.64 (1.07-2.51) | |
| Frequency of strenuous PA, d/wka | ||
| 0 | 1 [Reference] | .28 |
| 1-2 | 1.18 (0.72-1.94) | |
| 3 | 1.65 (0.99-2.73) | |
| ≥4 | 1.06 (0.51-2.20) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); HR, hazard ratio; PA, physical activity.
a
Duration and frequency variables were tested in separate adjusted models with similar HR estimates for remaining covariates.