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. Author manuscript; available in PMC: 2018 Dec 13.
Published in final edited form as: J Am Chem Soc. 2017 Nov 28;139(49):17707–17710. doi: 10.1021/jacs.7b09582

Table 2.

Scope with respect to the electrophile.

graphic file with name nihms-978051-t0012.jpg

entry electrophile yield (%)a
1 graphic file with name nihms-978051-t0013.jpg 80
2 graphic file with name nihms-978051-t0014.jpg 70
3 graphic file with name nihms-978051-t0015.jpg 65
4 graphic file with name nihms-978051-t0016.jpg 74
5 graphic file with name nihms-978051-t0017.jpg 55
6 graphic file with name nihms-978051-t0018.jpg 34
7b graphic file with name nihms-978051-t0019.jpg 41
8 graphic file with name nihms-978051-t0020.jpg 82
9b graphic file with name nihms-978051-t0021.jpg 56
10c graphic file with name nihms-978051-t0022.jpg 54
11d graphic file with name nihms-978051-t0023.jpg 61
a

Yields of purified product (average of two experiments).

b

Catalyst loading: 10% Cul, 20% rac-BINOL.

c

Starting material: cis/trans = 5/1; product: trans/cis >20/1.

d

Starting material: β/α >20/1; product: α/β >20/1.