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. Author manuscript; available in PMC: 2018 Dec 13.
Published in final edited form as: J Am Chem Soc. 2017 Nov 28;139(49):17707–17710. doi: 10.1021/jacs.7b09582

Table 3.

Scope with respect to the nucleophile.

graphic file with name nihms-978051-t0024.jpg

entry nucleophile yield (%)a
1 graphic file with name nihms-978051-t0025.jpg 83
2 graphic file with name nihms-978051-t0026.jpg 71
3 graphic file with name nihms-978051-t0027.jpg 70
4 graphic file with name nihms-978051-t0028.jpg 61
5b graphic file with name nihms-978051-t0029.jpg 84
6 graphic file with name nihms-978051-t0030.jpg 60
7b graphic file with name nihms-978051-t0031.jpg 75
8 graphic file with name nihms-978051-t0032.jpg 64
9 graphic file with name nihms-978051-t0033.jpg 52
10 graphic file with name nihms-978051-t0034.jpg 54
11 graphic file with name nihms-978051-t0035.jpg 80
a

Yields of purified product (average of two experiments).

b

Isolated as the trifluoroacetamide derivative.