Table 2. List of differently expressed spots during hypobaric hypoxia exposure, identified by MALDI-TOF/TOF.
| S. No. | Spot Id | Protein Name | Expected pI/MW | Gene Accession ID | Mascot Score | Species | Peptide sequence | Fold change# |
|---|---|---|---|---|---|---|---|---|
| 1 | 30820 | Aldolase B | 3.67 /40035 | gi|1619606 | 77 | Rattus | K.WRAVLR.I | -2.332 |
| 2 | 31316 | Cu-Zn Superoixde Dismutase | 4.95 /16155 | gi|155369696, | 46 | Rattus | R.MIQRLR.S | -4.2 |
| 3 | 30784 | Alcohol dehydrogenase [NADP+] | 6.84/ 36711 | gi|13591894 | 189 | Rattus |
R.SPAQILLR.W K.YALSVGYR.H |
-7.28 |
| 4 | 31162 | Glutathione–S–Transferase P | 9.02 / 23652 | gi|25453420 | 72 | Rattus | M.PPYTIVYFPVR.G | 3.55 |
| 5 | 30711 | T cell receptor V delta 6, | 8.84/31399 | gi|6724195 | 36 | Rattus | SGRYSVVFQK SLK | 2.88 |
| 6 | 30274 | E3 ubiquitin-protein ligase TTC3 | 6.11/225.79 | NP001101785 | 42 | Rattus | R.HLCQPR.G | 3.57 |
| 7 | 30428 | ATP synthase, H+ transporting, mitochondrial F1 complex | 7.04 / 5528.94 | gi|149029483 | 88 | Rattus | K.GPVGSKIR.R | -1.88 |
| 8 | 30660 | Actin, cytoplasmic 1 | 5.54 / 42.25 | gi|4501885 | 143 | Rattus | K.RGILTLK.Y | -1.287 |
| 9 | 31362 | Similar to microfilament and actin filament cross linker protein isoform | 5.5/612088 | gi 149023883 | 49 | Rattus |
R.INQLSAR.W R.NLQDSIK.R |
-1.2 |
| 10 | 31426 | Peptidyl‐prolyl cis‐trans isomerase A | 8.34/18091 | PPIA_RAT | 41 | Rattus | K.SIYGEKFEDENFILK.H | -2.28 |
| 11 | 30984 | Voltage‐dependent anion‐selective channel protein 1 | 8.62/30.8 | VDAC1_RAT | 88 | Rattus | R.EHINLGCDVDFDIAGPSIR.G | -1.35 |
| 12 | 31187 | Glutathione S‐transferase alpha‐3 | 8.78/25360 | GSTA3_RAT | 42 | Rattus | M.PGKPVLHYFDGR.G | -2.43 |
| 13 | 31677 | Haemoglobin alpha chain | 7.82/15490 | HBA_RAT | 164 | Rattus | K.LHVDPENFR.L | 7.191 |
| 14 | 31670 | Haemoglobin subunit beta |
7.88/16083 | HBB1_RAT | 150 | Rattus | K.IGGHGGEYGEEALQR.M | -1.50 |
| 15 | 31662 | Hemoglobin subunit Beta |
7.88/16083 | HBA_RAT | 174 | Rattus | K.IGGHGGEYGEEALQR.M | -1.77 |
| 16 | 31577 | Cytochrome c, somatic | 9.61/11712 | CYC_RAT | 64 | Rattus | K.TGPNLHGLFGR.K | -5.3 |
| 17 | 31753 | 10 kDa heat shock protein | 8.89/10895 | CH10_RAT | 73 | Rattus | K.VVLDDKDYFLFR.D | 4.25 |
| 18 | 30529 | ATP synthase subunit alpha, mitochondrial | 9.2/59831 | ATPA_RAT | 51 | Rattus | R.TGAIVDVPVGDELLGR.V | -1.26 |
| 19 | 30669 | Isocitrate dehydrogenase [NADP], mitochondrial | 8.88/51391 | IDHP_RAT | 62 | Rattus | R.GKLDGNQDLIR.F | -1.677 |
| 20 | 31667 | Hemoglobin subunit alpha‐1/2 | 7.82/15490 | HBA_RAT | 107 | Rattus | K.IGGHGGEYGEEALQR.M | 1.27 |
| 21 | 31687 | Hemoglobin subunit alpha‐1/2 | 7.82/15490 | HBA_RAT | 108 | Rattus | K.IGGHGGEYGEEALQR.M | 13.11 |
| 22 | 31661 | rCG34342, isoform CRA_b | 6. 64/15490 | EDM04010.1 | 48 | Rattus | K.IGGHGGEYGEEALQR.M | 5.319 |
Note:-
‘#’indicates P value less than 0.05 as compared to control group.