Table 4. List of pathways obtained by KEGG pathway enrichment analysis of some of these identified proteins.
| S. No. | Pathway involved | FDR# (False Discovery Rate) P-value |
Proteins involved |
|---|---|---|---|
| 1. | ATP metabolic process | 3.30E-26 | Atp5a1, Aldob |
| 2. | Oxidative phosphorylation | 1.37E-28 | Atp5a1 |
| 3 | Glycolysis / Gluconeogenesis | 1.04E-23 | Akr1a1, Aldob |
| 4 | Glutathione metabolism | 0.000231 | Gstp1 |
| 5 | Regulation of actin cytoskeleton | 0.0383 | Actb, |
| 6 | Carbon metabolism | 1.13E-21 | Aldob |
| 7 | Metabolism of xenobiotics by cytochrome P450 | 1.17E-10 | Gstp1 |
| 8 | Phagosome | 3.20E-08 | Aldob |
| 9. | Drug metabolism—cytochrome P450 | 1.55E-05 | Gstp1 |
| 10 | Removal of superoxide radicals | 0.0145 | Sod2, Sod3, Sod1 |
| 11 | Response to reactive oxygen species | 0.0306 | Gstp1, |
| 12 | Response to hypoxia | 0.0417 | Sod2, sod1 |
| 13. | Transport | 0.000241 | Atp5a1 |
| 14 | Response to stimulus | 0.00044 | Aldob, Gstp1, |
Note:-
‘#’indicates P value less than 0.05 as compared to control group.