Table 5. Effect of hypobaric hypoxia on pH, blood gas variables and blood electrolytes in 7 days hypobaric hypoxia exposed rats.
S. No. | Blood gas variables (Mixed venous blood) | Normoxia Control | 7 day hypoxia# |
---|---|---|---|
1. | pH | 7.371 ± 0.02520 | 7.157 ± 0.03251 ** |
2. | pCO2 (mmhg) | 67.13 ± 4.886 | 42.72 ± 2.044 ** |
3. | pO2 (mmhg) | 40.67 ± 0.3333 | 26.60 ± 3.945* |
4. | Base Excess (mmol/L) | 0.6667 ± 2.404 | -12.33 ± 2.092 ** |
5. | HCO3- (mmol/L) | 26.80 ± 2.822 | 16.22 ± 1.598 ** |
6. | T CO2 (mmhg) | 30.83 ± 3.941 | 17.50 ± 1.648 ** |
7. | SvO2 (%) | 68.97 ± 1.742 | 44.00 ± 6.528 * |
8. | Lactate (mmol/L) | 1.360 ± 0.3233 | 8.354 ± 1.837 * |
‘#’ Data represented here Mean ± S. E. M. (n = 5). Values are significant if P<0.05.
* stands for level of significance when P<0.05
**when P<0.05
*** when P<0.05 vs. normoxia control.