Table 2. Ligand-Based Pharmacophore Hypotheses and Their Scores.
| ID | survival | survival-inactive | site | vector | volume | selectivity | # matches | energy | activity | inactive |
|---|---|---|---|---|---|---|---|---|---|---|
| DDHRR.6 | 3.785 | 1.854 | 0.93 | 0.956 | 0.898 | 2.098 | 5 | 0 | 1.745 | 1.931 |
| DDHRR.5 | 3.668 | 1.715 | 0.89 | 0.928 | 0.847 | 2.096 | 5 | 0 | 1.824 | 1.953 |
| DDHRR.4 | 3.631 | 1.69 | 0.81 | 0.952 | 0.865 | 2.083 | 5 | 0.48 | 1.745 | 1.942 |
| DDHRR.3 | 3.032 | 1.181 | 0.6 | 0.641 | 0.792 | 2.092 | 5 | 1.736 | 1.824 | 1.851 |
| DDHRR.2 | 2.785 | 0.972 | 0.17 | 0.949 | 0.662 | 2.105 | 5 | 0.007 | 1.824 | 1.813 |
| DDHRR.1 | 2.676 | 0.908 | 0.14 | 0.905 | 0.626 | 2.091 | 5 | 0.486 | 1.824 | 1.768 |