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. 2017 Aug 30;2(8):5215–5220. doi: 10.1021/acsomega.7b00869

Figure 1.

Figure 1

Effect of protein kinase CK-1δ inhibitors on 6-hydroxydopamine (6-OHDA)-induced SH-SY5Y cell death. SH-SY5Y cells were exposed for 24 h to 6-OHDA (35 μM) in the presence or absence of the CK-1δ inhibitors (10 μM) (A) and compound 4 (0.1–20 μM) (B). The number of viable cells was measured by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Each data point represents the mean ± SD of six replications in three different experiments. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 statistically significant differences between CK-1δ inhibitors and 6-OHDA-treated cultures.