Table 3. Treatment regimens used and patient outcomes observed, by study group. Belém, Brazil, 2015.
| Variable | Groupa | p* | OR (95% CI) | |
|---|---|---|---|---|
| MABSC (n = 17) | NTM (n = 26) | |||
| Regimen usedb | ||||
| 1st regimen | 6 (35.3) | 20 (91.0)‡ | 1.0 | |
| 2nd regimen | 7 (41.2)† | 2 (9.0) | 0.0007 | 11.70 (1.9-71.8) |
| 3rd regimen | 4 (23.5)† | 0 (0.0) | - | |
| Primary outcomec (after 1st regimen) | ||||
| Clinical improvement and cure | 3 (17.6) | 20 (83.2)† | < 0.0001 | 1.00 |
| Dropout | 3 (17.6) | 2 (8.4) | 10.00 (1.2-86.9) | |
| Treatment failure | 11 (64.8)† | 2 (8.4) | 36.70 (5.3-253.8) | |
| Secondary outcome | ||||
| Clinical improvement and cure | 10 (91.0) | 2 (100) | 0.3917 | 1.0 |
| Death | 1 (9.0) | 0 (0.0) | - | |
MABSC: Mycobacterium abscessus complex; NTM: mycobacteria other than M. tuberculosis mycobacteria and MABSC; 1st regimen: rifampin, ethambutol, and clarithromycin; 2nd regimen: 1st regimen plus amikacin or streptomycin; and 3rd regimen: 2nd regimen plus imipenem. aValues expressed as n (%). bThe value of n is different in the NTM group because of two deaths and two dropouts for which there was no information on primary outcome. cThe value of n is different in the NTM group because of two deaths of unknown cause. *G-test and analysis of adjusted residuals, when necessary. †Cell with statistical significance.