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. 2017 Oct 6;2(10):6455–6463. doi: 10.1021/acsomega.7b01016

Figure 2.

Figure 2

(a) Schematic representation of trigger-dependent sustained release of a drug from a mixture of nanoparticles having varying trigger sensitivities. (b) Release of doxorubicin from nanogels. The release was triggered after 60 min by increasing the temperature of the system from 37 to 43 °C (indicated by the dotted line). (c) rf-dependent heating of AuNPs and core–shell nanoparticles at 150 W. 1:1 mix: mixture of pNIPAm and pNIPMAm50 nanoparticles in a 1:1 ratio; PBS: phosphate-buffered saline; pNIPAm: Au core with the pNIPAm shell; pNIPMAm50: Au core with the p(NIPAm-co-NIPMAm) shell with NIPAm/NIPMAm in the ratio of 1:1; Dox: doxorubicin. NG indicates only nanogels with compositions corresponding to the shells in the core–shell nanoparticles.