. 2016 Nov 16;1(5):923–929. doi: 10.1021/acsomega.6b00247

Table 4. Performance Measures in Predicting Pgp Inhibitors by Using All Inhibitor Data.

method	parameters	accuracy	sensitivity	specificity	κ	coverage
Training^a
v-NN	HC (h = 0.1; d₀ = 1.0)^b	0.83	0.87	0.77	0.65	1.00
v-NN	HA (h = 0.3; d₀ = 0.5)	0.87	0.93	0.74	0.68	0.75
Evaluation
v-NN	HC (h = 0.1; d₀ = 1.0)	0.77	0.88	0.66	0.54	1.00
v-NN	HA (h = 0.3; d₀ = 0.5)	0.81	0.92	0.69	0.62	0.81

Performance of 10-fold cross validation.

v-NN parameters (smoothing factor, h, and Tanimoto-distance threshold, d₀).