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| cell line |
|||
|---|---|---|---|
| BJ | U2OS | U2OS-R1 | |
| conjugate | EC50 [nM] | EC50 [nM] | EC50 [nM] |
| KCK-FGF2-(vcMMAE)3 | 48.2 ± 2.4 | 125.7 ± 47.5 | 2.2 ± 0.9 |
| FGF2-(vcMMAE)2 | 204.2 ± 23.0 | 1152.2 ± 56.5 | 4.1 ± 3.5 |
| KCK-FGF2[C78S/C96S]-(vcMMAE)1 | 450.6 ± 169.9 | 2358.3 ± 311.6 | 9.4 ± 5.4 |
| FGF2[C78S/C96S]-KCK-(vcMMAE)1 | 328.7 ± 53.3 | 774.6 ± 57.2 | 16.7 ± 2.9 |
