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. Author manuscript; available in PMC: 2018 Jul 13.
Published in final edited form as: Nat Protoc. 2018 Mar 29;13(5):819–839. doi: 10.1038/nprot.2017.148

Figure 4: Repli-seq allows the discrimination between haplotypes.

Figure 4:

A.: Comparison of RT in F121–9 mouse hybrid ES cells (M. musculus / M. castaneus hybrid cells). The mapping on the two genomes has been performed as described in Supplementary Method V, then log ratio datasets have been quantile normalized and Loess smoothed. Replication timing in 50kb windows for each allele and each replicate has been plotted using R. B.: Comparison of RT for three homologous regions in the same cells. Data are visualized using IGV. R = Pearson correlation coefficient.